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RNA-based cooperative protein labeling that permits direct monitoring of the intracellular concentration change of an endogenous protein

Imaging the dynamics of proteins in living cells is a powerful means for understanding cellular functions at a deeper level. Here, we report a versatile method for spatiotemporal imaging of specific endogenous proteins in living mammalian cells. The method employs a bifunctional aptamer capable of s...

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Detalles Bibliográficos
Autores principales: Pe, Kathleen Beverly Alog, Yatsuzuka, Kenji, Hakariya, Hayase, Kida, Tomoki, Katsuda, Yousuke, Fukuda, Masatora, Sato, Shin-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682759/
https://www.ncbi.nlm.nih.gov/pubmed/34581825
http://dx.doi.org/10.1093/nar/gkab839

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