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RNA-based cooperative protein labeling that permits direct monitoring of the intracellular concentration change of an endogenous protein
Imaging the dynamics of proteins in living cells is a powerful means for understanding cellular functions at a deeper level. Here, we report a versatile method for spatiotemporal imaging of specific endogenous proteins in living mammalian cells. The method employs a bifunctional aptamer capable of s...
Autores principales: | Pe, Kathleen Beverly Alog, Yatsuzuka, Kenji, Hakariya, Hayase, Kida, Tomoki, Katsuda, Yousuke, Fukuda, Masatora, Sato, Shin-ichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682759/ https://www.ncbi.nlm.nih.gov/pubmed/34581825 http://dx.doi.org/10.1093/nar/gkab839 |
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