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Cockayne syndrome group B protein regulates fork restart, fork progression and MRE11-dependent fork degradation in BRCA1/2-deficient cells

Cockayne syndrome group B (CSB) protein has been implicated in the repair of a variety of DNA lesions that induce replication stress. However, little is known about its role at stalled replication forks. Here, we report that CSB is recruited to stalled forks in a manner dependent upon its T1031 phos...

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Detalles Bibliográficos
Autores principales:	Batenburg, Nicole L, Mersaoui, Sofiane Y, Walker, John R, Coulombe, Yan, Hammond-Martel, Ian, Wurtele, Hugo, Masson, Jean-Yves, Zhu, Xu-Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682776/ https://www.ncbi.nlm.nih.gov/pubmed/34871413 http://dx.doi.org/10.1093/nar/gkab1173

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