Mechanisms of distinctive mismatch tolerance between Rad51 and Dmc1 in homologous recombination

Homologous recombination (HR) is a primary DNA double-strand breaks (DSBs) repair mechanism. The recombinases Rad51 and Dmc1 are highly conserved in the RecA family; Rad51 is mainly responsible for DNA repair in somatic cells during mitosis while Dmc1 only works during meiosis in germ cells. This sp...

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Detalles Bibliográficos
Autores principales: Xu, Jingfei, Zhao, Lingyun, Peng, Sijia, Chu, Huiying, Liang, Rui, Tian, Meng, Connell, Philip P, Li, Guohui, Chen, Chunlai, Wang, Hong-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682777/
https://www.ncbi.nlm.nih.gov/pubmed/34871438
http://dx.doi.org/10.1093/nar/gkab1141

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