Inhibitor of growth protein 3 epigenetically silences endogenous retroviral elements and prevents innate immune activation

Endogenous retroviruses (ERVs) are subject to transcriptional repression in adult tissues, in part to prevent autoimmune responses. However, little is known about the epigenetic silencing of ERV expression. Here, we describe a new role for inhibitor of growth family member 3 (ING3), to add to an eme...

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Detalles Bibliográficos
Autores principales: Song, Yanhua, Hou, Gaopeng, Diep, Jonathan, Ooi, Yaw Shin, Akopyants, Natalia S, Beverley, Stephen M, Carette, Jan E, Greenberg, Harry B, Ding, Siyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682784/
https://www.ncbi.nlm.nih.gov/pubmed/34791430
http://dx.doi.org/10.1093/nar/gkab1070

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