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Position 34 of tRNA is a discriminative element for m(5)C38 modification by human DNMT2

Dnmt2, a member of the DNA methyltransferase superfamily, catalyzes the formation of 5-methylcytosine at position 38 in the anticodon loop of tRNAs. Dnmt2 regulates many cellular biological processes, especially the production of tRNA-derived fragments and intergenerational transmission of paternal...

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Detalles Bibliográficos
Autores principales: Huang, Zhi-Xuan, Li, Jing, Xiong, Qing-Ping, Li, Hao, Wang, En-Duo, Liu, Ru-Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682788/
https://www.ncbi.nlm.nih.gov/pubmed/34871455
http://dx.doi.org/10.1093/nar/gkab1148

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