VID22 counteracts G-quadruplex-induced genome instability

Genome instability is a condition characterized by the accumulation of genetic alterations and is a hallmark of cancer cells. To uncover new genes and cellular pathways affecting endogenous DNA damage and genome integrity, we exploited a Synthetic Genetic Array (SGA)-based screen in yeast. Among the...

Descripción completa

Detalles Bibliográficos
Autores principales: Galati, Elena, Bosio, Maria C, Novarina, Daniele, Chiara, Matteo, Bernini, Giulia M, Mozzarelli, Alessandro M, García-Rubio, Maria L, Gómez-González, Belén, Aguilera, Andrés, Carzaniga, Thomas, Todisco, Marco, Bellini, Tommaso, Nava, Giulia M, Frigè, Gianmaria, Sertic, Sarah, Horner, David S, Baryshnikova, Anastasia, Manzari, Caterina, D’Erchia, Anna M, Pesole, Graziano, Brown, Grant W, Muzi-Falconi, Marco, Lazzaro, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682794/
https://www.ncbi.nlm.nih.gov/pubmed/34871443
http://dx.doi.org/10.1093/nar/gkab1156

Ejemplares similares

Ejemplares similares