Cargando…

Shexiang Tongxin Dropping Pill Protects Against Chronic Heart Failure in Mice via Inhibiting the ERK/MAPK and TGF-β Signaling Pathways

Background: Chronic heart failure (CHF) is a major public health problem with high mortality and morbidity worldwide. Shexiang Tongxin Dropping Pill (STDP) is a widely used traditional Chinese medicine preparation for coronary heart disease and growing evidence proves that STDP exerts beneficial eff...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Shuying, Liu, Hanbing, Fang, Qianqian, He, Houhong, Lu, Xiaoyan, Wang, Yi, Fan, Xiaohui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682969/ https://www.ncbi.nlm.nih.gov/pubmed/34925046 http://dx.doi.org/10.3389/fphar.2021.796354

Ejemplares similares

Efficacy of Shexiang Tongxin Dropping Pills in a Swine Model of Coronary Slow Flow
por: Bai, Yupeng, et al.
Publicado: (2022)

Shexiang Tongxin dropping pill protects against isoproterenol-induced myocardial ischemia in vivo and in vitro
por: Qi, Jianyong, et al.
Publicado: (2017)

Protective effects of Shexiang Tongxin Dropping Pill on pituitrin-induced acute myocardial ischemia in rats
por: Lin, Shan, et al.
Publicado: (2017)

Shexiang Tongxin Dropping Pill Improves Peripheral Microvascular Blood Flow via Cystathionine-γ-Lyase
por: Zhang, Yanda, et al.
Publicado: (2019)

Exploring the mechanism of Shexiang Tongxin dropping pill in the treatment of microvascular angina through network pharmacology and molecular docking
por: Chang, Chen, et al.
Publicado: (2022)

Shexiang Tongxin Dropping Pills Promote Macrophage Polarization-Induced Angiogenesis Against Coronary Microvascular Dysfunction via PI3K/Akt/mTORC1 Pathway
por: Lu, Xiangyu, et al.
Publicado: (2022)

Qualitative and Quantitative Analysis of the Major Constituents in Shexiang Tongxin Dropping Pill by HPLC-Q-TOF-MS/MS and UPLC-QqQ-MS/MS
por: Chen, Daxin, et al.
Publicado: (2015)

Effect of Shexiang Tongxin dropping pill on stable coronary artery disease patients with normal fractional flow reserve and coronary microvascular disease: A study protocol
por: Lu, Yanli, et al.
Publicado: (2020)

Effect of Musk Tongxin Dropping Pill on Myocardial Remodeling and Microcirculation Dysfunction in Diabetic Cardiomyopathy
por: Zhao, Jingjing, et al.
Publicado: (2021)

Shexiang Baoxin Pills for Coronary Heart Disease in Animal Models: Preclinical Evidence and Promoting Angiogenesis Mechanism
por: Zhang, Ke-Jian, et al.
Publicado: (2017)

Protective Effect of Shexiang Baoxin Pill on Myocardial Ischemia/Reperfusion Injury in Patients With STEMI
por: Qin, Haixia, et al.
Publicado: (2021)

Meta-analysis and trial sequential analysis of shexiang baoxin pill for coronary slow flow
por: Guo, Hongxin, et al.
Publicado: (2022)

Musk Tongxin Dripping Pills for treating Ticagrelor in Patients After Percutaneous Coronary Intervention: Echocardiography Combined with Untargeted Metabolomics
por: Nan, Lyu, et al.
Publicado: (2021)

Effects of Shexiang Baoxin Pill for Coronary Microvascular Function: A Systematic Review and Meta-Analysis
por: Wang, Mengxi, et al.
Publicado: (2021)

The effect of Shexiang Tongxin Dropping Pills on coronary microvascular dysfunction (CMVD) among those with a mental disorder and non-obstructive coronary artery disease based on stress cardiac magnetic resonance images: A study protocol
por: Tian, Jinfan, et al.
Publicado: (2020)

Network analysis combined with pharmacological evaluation strategy to reveal the mechanism of Tibetan medicine Wuwei Shexiang pills in treating rheumatoid arthritis
por: He, Qingxiu, et al.
Publicado: (2022)

Shexiang Baoxin Pill Corrects Metabolic Disorders in a Rat Model of Metabolic Syndrome by Targeting Mitochondria
por: Wei, Dan, et al.
Publicado: (2018)

Co-administration of Shexiang Baoxin Pill and Chemotherapy Drugs Potentiated Cancer Therapy by Vascular-Promoting Strategy
por: Yang, Liu-qing, et al.
Publicado: (2019)

LC-MS-based metabolomics reveals the mechanism of anti-gouty arthritis effect of Wuwei Shexiang pill
por: Lang, Jirui, et al.
Publicado: (2023)

Shexiang Baoxin Pill, Derived From the Traditional Chinese Medicine, Provides Protective Roles Against Cardiovascular Diseases
por: Lu, Li, et al.
Publicado: (2018)

Shexiang Baoxin Pills as an Adjuvant Treatment for Chronic Heart Failure: A System Review and Meta-Analysis
por: Dong, Taiwei, et al.
Publicado: (2018)

Shexiang Baoxin Pill, a Traditional Chinese Herbal Formula, Rescues the Cognitive Impairments in APP/PS1 Transgenic Mice
por: Hu, Wei-Hui, et al.
Publicado: (2020)

Efficacy and safety of Shexiang Baoxin Pill for stable coronary artery disease: A systematic review and meta-analysis of 42 randomized controlled trials
por: Wei, Jingjing, et al.
Publicado: (2022)

Single-nucleus ribonucleic acid-sequencing and spatial transcriptomics reveal the cardioprotection of Shexiang Baoxin Pill (SBP) in mice with myocardial ischemia-reperfusion injury
por: Lin, Wenyong, et al.
Publicado: (2023)

Efficacy of Shexiang Baoxin Pills for the treatment of unstable angina pectoris: Protocol of systemic review and meta-analysis
por: Chen, Huadong, et al.
Publicado: (2019)

Shexiang Baoxin Pill, a Formulated Chinese Herbal Mixture, Induces Neuronal Differentiation of PC12 Cells: A Signaling Triggered by Activation of Protein Kinase A
por: Xu, Miranda Li, et al.
Publicado: (2019)

Shexiang Baoxin Pill, a Proprietary Multi-Constituent Chinese Medicine, Prevents Locomotor and Cognitive Impairment Caused by Brain Ischemia and Reperfusion Injury in Rats: A Potential Therapy for Neuropsychiatric Sequelae of Stroke
por: Qin, Zong-Shi, et al.
Publicado: (2021)

Investigating the Pharmacological Mechanisms of SheXiang XinTongNing Against Coronary Heart Disease Based on Network Pharmacology and Experimental Evaluation
por: Jia, Li-ying, et al.
Publicado: (2021)

A network-based method for mechanistic investigation of Shexiang Baoxin Pill’s treatment of cardiovascular diseases
por: Fang, Hai-Yang, et al.
Publicado: (2017)

Shexiang Baoxin Pill for Acute Myocardial Infarction: Clinical Evidence and Molecular Mechanism of Antioxidative Stress
por: Guo, Jianbo, et al.
Publicado: (2021)

Therapeutic efficacy and safety of Shexiang Baoxin Pill combined with trimetazidine in elderly patients with heart failure secondary to ischaemic cardiomyopathy: A systematic review and meta-analysis
por: Wen, Jianxia, et al.
Publicado: (2018)

Shexiang Baoxin Pills Could Alleviate Isoproterenol-Induced Heart Failure Probably through its Inhibition of CaV1.2 Calcium Channel Currents
por: Wu, Jianwei, et al.
Publicado: (2022)

A Systematic Review and Meta-Analysis of the Efficacy and Safety of Xinbao Pill in Chronic Heart Failure
por: Wang, Yuanping, et al.
Publicado: (2022)

Metabolomic Strategy for Studying the Intervention and the Synergistic Effects of the Shexiang Baoxin Pill for Treating Myocardial Infarction in Rats
por: Xiang, Li, et al.
Publicado: (2013)

Therapeutic Efficacy of Shexiang Baoxin Pill Combined with Exercise in Patients with Heart Failure with Preserved Ejection Fraction: A Single-Center, Double-Blind, Randomized Controlled Trial
por: Liu, Si-pei, et al.
Publicado: (2022)

Efficacy and Safety of Shexiang Baoxin Pill for Coronary Heart Disease after Percutaneous Coronary Intervention: A Systematic Review and Meta-analysis
por: Wei, Jingjing, et al.
Publicado: (2021)

Identification of Pharmacokinetic Markers for Guanxin Danshen Drop Pills in Rats by Combination of Pharmacokinetics, Systems Pharmacology, and Pharmacodynamic Assays
por: Yao, Hong, et al.
Publicado: (2018)

Evaluation and clinical implications of interactions between compound Danshen dropping pill and warfarin associated with the epoxide hydrolase gene
por: Chen, Xixi, et al.
Publicado: (2023)

Protective effect of Qishen Yiqi dropping pills on the myocardium of rats with chronic heart failure
por: Lu, Yinghong, et al.
Publicado: (2019)

Neuroprotective effects of Ginkgo biloba dropping pills in Parkinson’s disease
por: Yu, Dingyi, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_o171e44aq2jpo326cb076n3udj