Alternative polyadenylation is a determinant of oncogenic Ras function

Alternative polyadenylation of mRNA has important but poorly understood roles in development and cancer. Activating mutations in the Ras oncogene are common drivers of many human cancers. From a screen for enhancers of activated Ras (let-60) in Caenorhabditis elegans, we identified cfim-1, a subunit...

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Detalles Bibliográficos
Autores principales: Subramanian, Aishwarya, Hall, Mathew, Hou, Huayun, Mufteev, Marat, Yu, Bin, Yuki, Kyoko E., Nishimura, Haruka, Sathaseevan, Anson, Lant, Benjamin, Zhai, Beibei, Ellis, James, Wilson, Michael D., Daugaard, Mads, Derry, W. Brent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682989/
https://www.ncbi.nlm.nih.gov/pubmed/34919436
http://dx.doi.org/10.1126/sciadv.abh0562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8682989/
https://www.ncbi.nlm.nih.gov/pubmed/34919436
http://dx.doi.org/10.1126/sciadv.abh0562

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