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Dalbavancin
Dalbavancin is a long-acting antimicrobial agent with an excellent in vitro activity against Gram-positive pathogens, including staphylococcal biofilms. The unusually long terminal half-life ranging from 149 to 250 hours in human subjects, allows a weekly dose. Currently is indicated in acute bacter...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedad Española de Quimioterapia
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683005/ https://www.ncbi.nlm.nih.gov/pubmed/34598419 http://dx.doi.org/10.37201/req/s01.07.2021 |
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author | Barberán, José de la Cuerda, Alicia Barberán, Lourdes Cristina |
author_facet | Barberán, José de la Cuerda, Alicia Barberán, Lourdes Cristina |
author_sort | Barberán, José |
collection | PubMed |
description | Dalbavancin is a long-acting antimicrobial agent with an excellent in vitro activity against Gram-positive pathogens, including staphylococcal biofilms. The unusually long terminal half-life ranging from 149 to 250 hours in human subjects, allows a weekly dose. Currently is indicated in acute bacterial skin and skin structure infections (ABSSSIs), but in real-life clinical practice it has already been used successfully and safely in other infections, especially as consolidation therapy. |
format | Online Article Text |
id | pubmed-8683005 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Sociedad Española de Quimioterapia |
record_format | MEDLINE/PubMed |
spelling | pubmed-86830052021-12-29 Dalbavancin Barberán, José de la Cuerda, Alicia Barberán, Lourdes Cristina Rev Esp Quimioter Update on Antimicrobial Pharmacotherapy Dalbavancin is a long-acting antimicrobial agent with an excellent in vitro activity against Gram-positive pathogens, including staphylococcal biofilms. The unusually long terminal half-life ranging from 149 to 250 hours in human subjects, allows a weekly dose. Currently is indicated in acute bacterial skin and skin structure infections (ABSSSIs), but in real-life clinical practice it has already been used successfully and safely in other infections, especially as consolidation therapy. Sociedad Española de Quimioterapia 2021-09-30 2021 /pmc/articles/PMC8683005/ /pubmed/34598419 http://dx.doi.org/10.37201/req/s01.07.2021 Text en © The Author 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)(https://creativecommons.org/licenses/by-nc/4.0/). |
spellingShingle | Update on Antimicrobial Pharmacotherapy Barberán, José de la Cuerda, Alicia Barberán, Lourdes Cristina Dalbavancin |
title | Dalbavancin |
title_full | Dalbavancin |
title_fullStr | Dalbavancin |
title_full_unstemmed | Dalbavancin |
title_short | Dalbavancin |
title_sort | dalbavancin |
topic | Update on Antimicrobial Pharmacotherapy |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683005/ https://www.ncbi.nlm.nih.gov/pubmed/34598419 http://dx.doi.org/10.37201/req/s01.07.2021 |
work_keys_str_mv | AT barberanjose dalbavancin AT delacuerdaalicia dalbavancin AT barberanlourdescristina dalbavancin |