Cargando…
Comprehensive analysis of spatial architecture in primary liver cancer
Heterogeneity is the major challenge for cancer prevention and therapy. Here, we first constructed high-resolution spatial transcriptomes of primary liver cancers (PLCs) containing 84,823 spots within 21 tissues from seven patients. The progressive comparison of spatial tumor microenvironment (TME)...
Autores principales: | Wu, Rui, Guo, Wenbo, Qiu, Xinyao, Wang, Shicheng, Sui, Chengjun, Lian, Qiuyu, Wu, Jianmin, Shan, Yiran, Yang, Zhao, Yang, Shuai, Wu, Tong, Wang, Kaiting, Zhu, Yanjing, Wang, Shan, Liu, Changyi, Zhang, Yangqianwen, Zheng, Bo, Li, Zhixuan, Zhang, Yani, Shen, Siyun, Zhao, Yan, Wang, Wenwen, Bao, Jinxia, Hu, Ji, Wu, Xuan, Jiang, Xiaoqing, Wang, Hongyang, Gu, Jin, Chen, Lei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683021/ https://www.ncbi.nlm.nih.gov/pubmed/34919432 http://dx.doi.org/10.1126/sciadv.abg3750 |
Ejemplares similares
-
Single-cell atlas of diverse immune populations in the advanced biliary tract cancer microenvironment
por: Shi, Xuebing, et al.
Publicado: (2022) -
The identification and functional analysis of CD8+PD-1+CD161+ T cells in hepatocellular carcinoma
por: Li, Zhixuan, et al.
Publicado: (2020) -
Hepatobiliary Tumor Organoids Reveal HLA Class I Neoantigen Landscape and Antitumoral Activity of Neoantigen Peptide Enhanced with Immune Checkpoint Inhibitors
por: Wang, Wenwen, et al.
Publicado: (2022) -
Trajectory and Functional Analysis of PD‐1(high) CD4(+)CD8(+) T Cells in Hepatocellular Carcinoma by Single‐Cell Cytometry and Transcriptome Sequencing
por: Zheng, Bo, et al.
Publicado: (2020) -
Use of intercellular proximity labeling to quantify and decipher cell-cell interactions directed by diversified molecular pairs
por: Qiu, Shuang, et al.
Publicado: (2022)