Cargando…
NMNAT promotes glioma growth through regulating post-translational modifications of P53 to inhibit apoptosis
Gliomas are highly malignant brain tumors with poor prognosis and short survival. NAD(+) has been shown to impact multiple processes that are dysregulated in cancer; however, anti-cancer therapies targeting NAD(+) synthesis have had limited success due to insufficient mechanistic understanding. Here...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683086/ https://www.ncbi.nlm.nih.gov/pubmed/34919052 http://dx.doi.org/10.7554/eLife.70046 |