Venetoclax in Previously Treated Waldenström Macroglobulinemia

PURPOSE: BCL2 is overexpressed and confers prosurvival signaling in malignant lymphoplasmacytic cells in Waldenström macroglobulinemia (WM). Venetoclax is a potent BCL2 antagonist and triggers in vitro apoptosis of WM cells. The activity of venetoclax in WM remains to be clarified. PATIENTS AND METH...

Descripción completa

Detalles Bibliográficos
Autores principales: Castillo, Jorge J., Allan, John N., Siddiqi, Tanya, Advani, Ranjana H., Meid, Kirsten, Leventoff, Carly, White, Timothy P., Flynn, Catherine A., Sarosiek, Shayna, Branagan, Andrew R., Demos, Maria G., Guerrera, Maria L., Kofides, Amanda, Liu, Xia, Munshi, Manit, Tsakmaklis, Nicholas, Xu, Lian, Yang, Guang, Patterson, Christopher J., Hunter, Zachary R., Davids, Matthew S., Furman, Richard R., Treon, Steven P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2022
Materias:
ORIGINAL REPORTS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683218/
https://www.ncbi.nlm.nih.gov/pubmed/34793256
http://dx.doi.org/10.1200/JCO.21.01194

Ejemplares similares

Ejemplares similares