Discovery of ultrapotent broadly neutralizing antibodies from SARS-CoV-2 elite neutralizers

A fraction of COVID-19 convalescent individuals mount a potent antibody response to SARS-CoV-2 with cross-reactivity to SARS-CoV-1. To uncover their humoral response in detail, we performed single B cell analysis from 10 SARS-CoV-2 elite neutralizers. We isolated and analyzed 126 monoclonal antibodi...

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Detalles Bibliográficos
Autores principales: Vanshylla, Kanika, Fan, Chengcheng, Wunsch, Marie, Poopalasingam, Nareshkumar, Meijers, Matthijs, Kreer, Christoph, Kleipass, Franziska, Ruchnewitz, Denis, Ercanoglu, Meryem S., Gruell, Henning, Münn, Friederike, Pohl, Kai, Janicki, Hanna, Nolden, Tobias, Bartl, Simone, Stein, Saskia C., Augustin, Max, Dewald, Felix, Gieselmann, Lutz, Schommers, Philipp, Schulz, Thomas F., Sander, Leif Erik, Koch, Manuel, Łuksza, Marta, Lässig, Michael, Bjorkman, Pamela J., Klein, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683262/
https://www.ncbi.nlm.nih.gov/pubmed/34973165
http://dx.doi.org/10.1016/j.chom.2021.12.010

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