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EpoR stimulates rapid cycling and larger red cells during mouse and human erythropoiesis
The erythroid terminal differentiation program couples sequential cell divisions with progressive reductions in cell size. The erythropoietin receptor (EpoR) is essential for erythroblast survival, but its other functions are not well characterized. Here we use Epor(−/−) mouse erythroblasts endowed...
Autores principales: | Hidalgo, Daniel, Bejder, Jacob, Pop, Ramona, Gellatly, Kyle, Hwang, Yung, Maxwell Scalf, S., Eastman, Anna E., Chen, Jane-Jane, Zhu, Lihua Julie, Heuberger, Jules A. A. C., Guo, Shangqin, Koury, Mark J., Nordsborg, Nikolai Baastrup, Socolovsky, Merav |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683474/ https://www.ncbi.nlm.nih.gov/pubmed/34921133 http://dx.doi.org/10.1038/s41467-021-27562-4 |
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