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High TGF-β signature predicts immunotherapy resistance in gynecologic cancer patients treated with immune checkpoint inhibition

Various immune signatures predictive of resistance to immune checkpoint inhibitors (ICI) have been described in multiple solid cancers, but still under-investigated in gynecological (GYN) cancer. For 49 GYN cancer patients included in our study, without transcriptome signature, immune-related toxici...

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Detalles Bibliográficos
Autores principales: Ni, Ying, Soliman, Ahmed, Joehlin-Price, Amy, Rose, Peter G., Vlad, Anda, Edwards, Robert P., Mahdi, Haider
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683510/
https://www.ncbi.nlm.nih.gov/pubmed/34921236
http://dx.doi.org/10.1038/s41698-021-00242-8