Conditional gene targeting using UCP1-Cre mice directly targets the central nervous system beyond thermogenic adipose tissues

OBJECTIVE: Uncoupling protein 1 (UCP1) is a mitochondrial protein critical for adaptive thermogenesis in adipose tissues, and it is typically believed to be restricted to thermogenic adipose tissues. UCP1-Cre transgenic mice are utilized in numerous studies to provide “brown adipose-specific” condit...

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Detalles Bibliográficos
Autores principales: Claflin, Kristin E., Flippo, Kyle H., Sullivan, Andrew I., Naber, Meghan C., Zhou, Bolu, Neff, Tate J., Jensen-Cody, Sharon O., Potthoff, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683614/
https://www.ncbi.nlm.nih.gov/pubmed/34844020
http://dx.doi.org/10.1016/j.molmet.2021.101405

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