SGLT‐1‐specific inhibition ameliorates renal failure and alters the gut microbial community in mice with adenine‐induced renal failure

Sodium‐dependent glucose cotransporters (SGLTs) have attracted considerable attention as new targets for type 2 diabetes mellitus. In the kidney, SGLT2 is the major glucose uptake transporter in the proximal tubules, and inhibition of SGLT2 in the proximal tubules shows renoprotective effects. On th...

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Detalles Bibliográficos
Autores principales: Ho, Hsin‐Jung, Kikuchi, Koichi, Oikawa, Daiki, Watanabe, Shun, Kanemitsu, Yoshitomi, Saigusa, Daisuke, Kujirai, Ryota, Ikeda‐Ohtsubo, Wakako, Ichijo, Mariko, Akiyama, Yukako, Aoki, Yuichi, Mishima, Eikan, Ogata, Yoshiaki, Oikawa, Yoshitsugu, Matsuhashi, Tetsuro, Toyohara, Takafumi, Suzuki, Chitose, Suzuki, Takehiro, Mano, Nariyasu, Kagawa, Yoshiteru, Owada, Yuji, Katayama, Takane, Nakayama, Toru, Tomioka, Yoshihisa, Abe, Takaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683788/
https://www.ncbi.nlm.nih.gov/pubmed/34921520
http://dx.doi.org/10.14814/phy2.15092

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