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Predictors of death in patients with COVID-19: A cross-sectional study in West of Iran

Background: Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a newly identified coronavirus. Our knowledge about the survival rate and prognostic factors of the disease is not established well. The purpose of this study was to evaluate the predictors of COVID-19 mortality in Ham...

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Autores principales: Karami, Manoochehr, Mirzaei, Mohammad, Shahbazi, Fatemeh, Keramat, Fariba, Jalili, Ebrahim, Bashirian, Saeid, Heidarimoghadam, Rashid, Bathaei, Jalal, Khazaei, Salman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iran University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683832/
https://www.ncbi.nlm.nih.gov/pubmed/34956949
http://dx.doi.org/10.47176/mjiri.35.103
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author Karami, Manoochehr
Mirzaei, Mohammad
Shahbazi, Fatemeh
Keramat, Fariba
Jalili, Ebrahim
Bashirian, Saeid
Heidarimoghadam, Rashid
Bathaei, Jalal
Khazaei, Salman
author_facet Karami, Manoochehr
Mirzaei, Mohammad
Shahbazi, Fatemeh
Keramat, Fariba
Jalili, Ebrahim
Bashirian, Saeid
Heidarimoghadam, Rashid
Bathaei, Jalal
Khazaei, Salman
author_sort Karami, Manoochehr
collection PubMed
description Background: Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a newly identified coronavirus. Our knowledge about the survival rate and prognostic factors of the disease is not established well. The purpose of this study was to evaluate the predictors of COVID-19 mortality in Hamadan province in western Iran. Methods: In this study, we included all laboratory-confirmed COVID-19 cases with known treatment outcomes in Hamadan province, Iran, between 20, 2020, to May 10, 2020. Demographic, clinical, laboratory data, and treatment outcomes were obtained from computerized medical records and compared between survived cases and patients with death outcomes. Univariable and multivariable logistic regression models were used to determine the predictors of death. Results: From 749 investigated patients, 77 patients (10.28%) died during the treatment. The Mean age of patients was 53.97±19.04 years. Multivariable logistic regression showed that males had 2.07 (95% CI: 1.73, 2.54) fold higher odds of death. Those with 60 years old and more had 6.49 (95% CI: 4.53, 7.93) fold higher odds of death. Patients with an underlying disease had 7.14 (95% CI: 6.94, 7.38) fold higher odds of death, and patients who were hospitalized in the ICU ward had 2.24 (95% CI: 1.75, 2.90) times higher odds of COVID-19 related mortality. Conclusion: The potential predictors of death in COVID-19 cases, including the male gender, older age, and having an underlying disease could help physicians to identify patients with poor prognoses at an early stage and better management of them.
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spelling pubmed-86838322021-12-23 Predictors of death in patients with COVID-19: A cross-sectional study in West of Iran Karami, Manoochehr Mirzaei, Mohammad Shahbazi, Fatemeh Keramat, Fariba Jalili, Ebrahim Bashirian, Saeid Heidarimoghadam, Rashid Bathaei, Jalal Khazaei, Salman Med J Islam Repub Iran Original Article Background: Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a newly identified coronavirus. Our knowledge about the survival rate and prognostic factors of the disease is not established well. The purpose of this study was to evaluate the predictors of COVID-19 mortality in Hamadan province in western Iran. Methods: In this study, we included all laboratory-confirmed COVID-19 cases with known treatment outcomes in Hamadan province, Iran, between 20, 2020, to May 10, 2020. Demographic, clinical, laboratory data, and treatment outcomes were obtained from computerized medical records and compared between survived cases and patients with death outcomes. Univariable and multivariable logistic regression models were used to determine the predictors of death. Results: From 749 investigated patients, 77 patients (10.28%) died during the treatment. The Mean age of patients was 53.97±19.04 years. Multivariable logistic regression showed that males had 2.07 (95% CI: 1.73, 2.54) fold higher odds of death. Those with 60 years old and more had 6.49 (95% CI: 4.53, 7.93) fold higher odds of death. Patients with an underlying disease had 7.14 (95% CI: 6.94, 7.38) fold higher odds of death, and patients who were hospitalized in the ICU ward had 2.24 (95% CI: 1.75, 2.90) times higher odds of COVID-19 related mortality. Conclusion: The potential predictors of death in COVID-19 cases, including the male gender, older age, and having an underlying disease could help physicians to identify patients with poor prognoses at an early stage and better management of them. Iran University of Medical Sciences 2021-08-11 /pmc/articles/PMC8683832/ /pubmed/34956949 http://dx.doi.org/10.47176/mjiri.35.103 Text en © 2021 Iran University of Medical Sciences https://creativecommons.org/licenses/by-nc-sa/1.0/This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial-ShareAlike 1.0 License (CC BY-NC-SA 1.0), which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Original Article
Karami, Manoochehr
Mirzaei, Mohammad
Shahbazi, Fatemeh
Keramat, Fariba
Jalili, Ebrahim
Bashirian, Saeid
Heidarimoghadam, Rashid
Bathaei, Jalal
Khazaei, Salman
Predictors of death in patients with COVID-19: A cross-sectional study in West of Iran
title Predictors of death in patients with COVID-19: A cross-sectional study in West of Iran
title_full Predictors of death in patients with COVID-19: A cross-sectional study in West of Iran
title_fullStr Predictors of death in patients with COVID-19: A cross-sectional study in West of Iran
title_full_unstemmed Predictors of death in patients with COVID-19: A cross-sectional study in West of Iran
title_short Predictors of death in patients with COVID-19: A cross-sectional study in West of Iran
title_sort predictors of death in patients with covid-19: a cross-sectional study in west of iran
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8683832/
https://www.ncbi.nlm.nih.gov/pubmed/34956949
http://dx.doi.org/10.47176/mjiri.35.103
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