Solubility Enhancement of Antidiabetic Drugs Using a Co‐Crystallization Approach

The co‐crystallization approach has been used to enhance specific desirable properties of active pharmaceutical ingredients (APIs) such as solubility, dissolution rate, and stability. Solubility is a fundamental property that affects the bioavailability and dosage of the API. The co‐crystal approach...

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Detalles Bibliográficos
Autor principal: Batisai, Eustina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684040/
https://www.ncbi.nlm.nih.gov/pubmed/34921592
http://dx.doi.org/10.1002/open.202100246
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author Batisai, Eustina
author_facet Batisai, Eustina
author_sort Batisai, Eustina
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description The co‐crystallization approach has been used to enhance specific desirable properties of active pharmaceutical ingredients (APIs) such as solubility, dissolution rate, and stability. Solubility is a fundamental property that affects the bioavailability and dosage of the API. The co‐crystal approach is one of the emerging methods with the potential for improving the solubility of these drugs. This paper reviews the latest progress on improving the solubility of some antidiabetic drug molecules using the co‐crystal approach.
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spelling pubmed-86840402021-12-30 Solubility Enhancement of Antidiabetic Drugs Using a Co‐Crystallization Approach Batisai, Eustina ChemistryOpen Reviews The co‐crystallization approach has been used to enhance specific desirable properties of active pharmaceutical ingredients (APIs) such as solubility, dissolution rate, and stability. Solubility is a fundamental property that affects the bioavailability and dosage of the API. The co‐crystal approach is one of the emerging methods with the potential for improving the solubility of these drugs. This paper reviews the latest progress on improving the solubility of some antidiabetic drug molecules using the co‐crystal approach. John Wiley and Sons Inc. 2021-12-18 /pmc/articles/PMC8684040/ /pubmed/34921592 http://dx.doi.org/10.1002/open.202100246 Text en © 2021 The Authors. Published by Wiley-VCH GmbH https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Reviews
Batisai, Eustina
Solubility Enhancement of Antidiabetic Drugs Using a Co‐Crystallization Approach
title Solubility Enhancement of Antidiabetic Drugs Using a Co‐Crystallization Approach
title_full Solubility Enhancement of Antidiabetic Drugs Using a Co‐Crystallization Approach
title_fullStr Solubility Enhancement of Antidiabetic Drugs Using a Co‐Crystallization Approach
title_full_unstemmed Solubility Enhancement of Antidiabetic Drugs Using a Co‐Crystallization Approach
title_short Solubility Enhancement of Antidiabetic Drugs Using a Co‐Crystallization Approach
title_sort solubility enhancement of antidiabetic drugs using a co‐crystallization approach
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684040/
https://www.ncbi.nlm.nih.gov/pubmed/34921592
http://dx.doi.org/10.1002/open.202100246
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