Immunogenicity profile in African green monkeys of a vaccine candidate based on a mutated form of human Interleukin-15

BACKGROUND: Interleukin (IL)-15 is a proinflammatory T-cell growth factor overexpressed in several autoimmune diseases such as rheumatoid arthritis. Our initial strategy to neutralize the increased levels of IL-15 consisted in a vaccine candidate based on the recombinant modified human IL-15 (mhIL-1...

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Detalles Bibliográficos
Autores principales: Rodríguez-Álvarez, Yunier, Batista-Roche, Lino Gerardo, Llopiz-Arzuaga, Alexey, Puente-Pérez, Pedro, Martínez-Castillo, Rafael, Castro-Velazco, Jorge, Santos-Savio, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684083/
https://www.ncbi.nlm.nih.gov/pubmed/34922462
http://dx.doi.org/10.1186/s12865-021-00470-4

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