MiR-212-3p functions as a tumor suppressor gene in group 3 medulloblastoma via targeting nuclear factor I/B (NFIB)

Haploinsufficiency of chromosome 17p and c-Myc amplification distinguish group 3 medulloblastomas which are associated with early metastasis, rapid recurrence, and swift mortality. Tumor suppressor genes on this locus have not been adequately characterized. We elucidated the role of miR-212-3p in th...

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Detalles Bibliográficos
Autores principales: Perumal, Naveenkumar, Kanchan, Ranjana K., Doss, David, Bastola, Noah, Atri, Pranita, Chirravuri-Venkata, Ramakanth, Thapa, Ishwor, Vengoji, Raghupathy, Maurya, Shailendra K., Klinkebiel, David, Talmon, Geoffrey A., Nasser, Mohd W., Batra, Surinder K., Mahapatra, Sidharth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684142/
https://www.ncbi.nlm.nih.gov/pubmed/34922631
http://dx.doi.org/10.1186/s40478-021-01299-z

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