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Quantitative single-cell analysis of immunofluorescence protein multiplex images illustrates biomarker spatial heterogeneity within breast cancer subtypes

BACKGROUND: The extent of cellular heterogeneity in breast cancer could have potential impact on diagnosis and long-term outcome. However, pathology evaluation is limited to biomarker immunohistochemical staining and morphology of the bulk cancer. Inter-cellular heterogeneity of biomarkers is not us...

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Detalles Bibliográficos
Autores principales:	Cheung, Alison Min-Yan, Wang, Dan, Liu, Kela, Hope, Tyna, Murray, Mayan, Ginty, Fiona, Nofech-Mozes, Sharon, Martel, Anne Louise, Yaffe, Martin Joel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684264/ https://www.ncbi.nlm.nih.gov/pubmed/34922607 http://dx.doi.org/10.1186/s13058-021-01475-y

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