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CircIL4R activates the PI3K/AKT signaling pathway via the miR-761/TRIM29/PHLPP1 axis and promotes proliferation and metastasis in colorectal cancer

BACKGROUND: Accumulating studies have revealed that aberrant expression of circular RNAs (circRNAs) is widely involved in the tumorigenesis and progression of malignant cancers, including colorectal cancer (CRC). Nevertheless, the clinical significance, levels, features, biological function, and mol...

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Detalles Bibliográficos
Autores principales: Jiang, Tao, Wang, Hongyu, Liu, Lianyu, Song, Hu, Zhang, Yi, Wang, Jiaqi, Liu, Lei, Xu, Teng, Fan, Ruizhi, Xu, Yixin, Wang, Shuai, Shi, Linsen, Zheng, Li, Wang, Renhao, Song, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684286/
https://www.ncbi.nlm.nih.gov/pubmed/34922544
http://dx.doi.org/10.1186/s12943-021-01474-9

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