Potentiating the Cytotoxic Activity of a Novel Simvastatin-Loaded Cubosome against Breast Cancer Cells: Insights on Dual Cell Death via Ferroptosis and Apoptosis

PURPOSE: Female breast cancer is the most prevalent cancer worldwide. Emerging evidence shows that simvastatin (SIM) has promising anticancer activities. However, the underlying mechanisms are not fully elucidated. Increasing reports imply statins can modulate ferroptosis through disrupting reactive...

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Detalles Bibliográficos
Autores principales: Elakkad, Yara E, Mohamed, Shimaa Nabil Senousy, Abuelezz, Nermeen Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684378/
https://www.ncbi.nlm.nih.gov/pubmed/34934357
http://dx.doi.org/10.2147/BCTT.S336712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684378/
https://www.ncbi.nlm.nih.gov/pubmed/34934357
http://dx.doi.org/10.2147/BCTT.S336712

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