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Oral Immunotherapy in Children: Clinical Considerations and Practical Management
Oral immunotherapy (OIT) in pediatric patients provides an alternative option to the current standard of care in food allergy, which is allergen avoidance and reactive treatment. Because patients are exposed to one or more food allergens during treatment, OIT is associated with adverse events and ca...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684389/ https://www.ncbi.nlm.nih.gov/pubmed/34934327 http://dx.doi.org/10.2147/JAA.S282696 |
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author | Anderson, Brent Wong, Lauren Adlou, Bahman Long, Andrew Chinthrajah, R Sharon |
author_facet | Anderson, Brent Wong, Lauren Adlou, Bahman Long, Andrew Chinthrajah, R Sharon |
author_sort | Anderson, Brent |
collection | PubMed |
description | Oral immunotherapy (OIT) in pediatric patients provides an alternative option to the current standard of care in food allergy, which is allergen avoidance and reactive treatment. Because patients are exposed to one or more food allergens during treatment, OIT is associated with adverse events and can be a cumbersome process for children, their caregivers, and clinicians. However, there have been an overwhelming number of studies that show high efficacy in both single- and multi-allergen OIT, and that quality of life is greatly improved for both patients and their families after undergoing immunotherapy. This review discusses clinical considerations for OIT in pediatrics, including efficacy and safety, practical management, and future directions of treatment. |
format | Online Article Text |
id | pubmed-8684389 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-86843892021-12-20 Oral Immunotherapy in Children: Clinical Considerations and Practical Management Anderson, Brent Wong, Lauren Adlou, Bahman Long, Andrew Chinthrajah, R Sharon J Asthma Allergy Review Oral immunotherapy (OIT) in pediatric patients provides an alternative option to the current standard of care in food allergy, which is allergen avoidance and reactive treatment. Because patients are exposed to one or more food allergens during treatment, OIT is associated with adverse events and can be a cumbersome process for children, their caregivers, and clinicians. However, there have been an overwhelming number of studies that show high efficacy in both single- and multi-allergen OIT, and that quality of life is greatly improved for both patients and their families after undergoing immunotherapy. This review discusses clinical considerations for OIT in pediatrics, including efficacy and safety, practical management, and future directions of treatment. Dove 2021-12-14 /pmc/articles/PMC8684389/ /pubmed/34934327 http://dx.doi.org/10.2147/JAA.S282696 Text en © 2021 Anderson et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Review Anderson, Brent Wong, Lauren Adlou, Bahman Long, Andrew Chinthrajah, R Sharon Oral Immunotherapy in Children: Clinical Considerations and Practical Management |
title | Oral Immunotherapy in Children: Clinical Considerations and Practical Management |
title_full | Oral Immunotherapy in Children: Clinical Considerations and Practical Management |
title_fullStr | Oral Immunotherapy in Children: Clinical Considerations and Practical Management |
title_full_unstemmed | Oral Immunotherapy in Children: Clinical Considerations and Practical Management |
title_short | Oral Immunotherapy in Children: Clinical Considerations and Practical Management |
title_sort | oral immunotherapy in children: clinical considerations and practical management |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684389/ https://www.ncbi.nlm.nih.gov/pubmed/34934327 http://dx.doi.org/10.2147/JAA.S282696 |
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