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Current Opinions on the Clinical Utility of Ravulizumab for the Treatment of Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disorder of hematopoietic stem cells genetically defined by the acquisition of somatic mutations in the X-linked phosphatidylinositol glycan anchor biosynthesis, class A (PIGA) gene. PIGA is essential for the synthesis of glycosyl phosphatidylinosi...

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Detalles Bibliográficos
Autores principales: Gurnari, Carmelo, Nautiyal, Ishani, Pagliuca, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684432/
https://www.ncbi.nlm.nih.gov/pubmed/34934322
http://dx.doi.org/10.2147/TCRM.S273360