A Nanoparticle-Conjugated Anti-TBK1 siRNA Induces Autophagy-Related Apoptosis and Enhances cGAS-STING Pathway in GBM Cells

BACKGROUND: Gene therapy shows considerable clinical benefit in cancer therapy, in which single-stranded ribonucleic acid (siRNA) is a promising strategy in the treatment of glioblastoma (GBM). TANK-binding kinase 1 (TBK1) is critical in tumorigenesis and development, which lays a foundation for an...

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Detalles Bibliográficos
Autores principales: Xu, Shengchao, Yan, Xi, Tang, Lu, Dai, Gan, Luo, Chengke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684524/
https://www.ncbi.nlm.nih.gov/pubmed/34931127
http://dx.doi.org/10.1155/2021/6521953

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