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Loss of miR-24-3p promotes epithelial cell apoptosis and impairs the recovery from intestinal inflammation
While apoptosis plays a significant role in intestinal homeostasis, it can also be pathogenic if overactive during recovery from inflammation. We recently reported that microRNA-24-3p (miR-24-3p) is elevated in the colonic epithelium of ulcerative colitis patients during active inflammation, and tha...
Autores principales: | Soroosh, Artin, Fang, Kai, Hoffman, Jill M., Law, Ivy K. M., Videlock, Elizabeth, Lokhandwala, Zulfiqar A., Zhao, Jonathan J., Hamidi, Sepehr, Padua, David M., Frey, Mark R., Pothoulakis, Charalabos, Rankin, Carl R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684555/ https://www.ncbi.nlm.nih.gov/pubmed/34923573 http://dx.doi.org/10.1038/s41419-021-04463-4 |
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