Promoter methylation-mediated repression of UNC5 receptors and the associated clinical significance in human colorectal cancer

BACKGROUND: Deregulated methylation of tumor suppressor genes is a hallmark event in colorectal cancer (CRC) carcinogenesis. UNC5 receptors, down-regulated in various human malignancies due to epigenetic alterations, have been proposed as putative tumor suppressor genes. In this study, we focused on...

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Detalles Bibliográficos
Autores principales: Dong, Dong, Zhang, Runshi, Shao, Jie, Zhang, Aimin, Wang, Yichao, Zhou, Yunli, Li, Yueguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684698/
https://www.ncbi.nlm.nih.gov/pubmed/34922605
http://dx.doi.org/10.1186/s13148-021-01211-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684698/
https://www.ncbi.nlm.nih.gov/pubmed/34922605
http://dx.doi.org/10.1186/s13148-021-01211-5

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