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Promoter methylation-mediated repression of UNC5 receptors and the associated clinical significance in human colorectal cancer
BACKGROUND: Deregulated methylation of tumor suppressor genes is a hallmark event in colorectal cancer (CRC) carcinogenesis. UNC5 receptors, down-regulated in various human malignancies due to epigenetic alterations, have been proposed as putative tumor suppressor genes. In this study, we focused on...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684698/ https://www.ncbi.nlm.nih.gov/pubmed/34922605 http://dx.doi.org/10.1186/s13148-021-01211-5 |