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Substratum stiffness signals through integrin-linked kinase and β1-integrin to regulate midbody proteins and abscission during EMT

Abscission is the final stage of cytokinesis during which the parent cell physically separates to yield two identical daughters. Failure of abscission results in multinucleation (MNC), a sign of genomic instability and a precursor to aneuploidy, enabling characteristics of neoplastic progression. In...

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Detalles Bibliográficos
Autores principales:	Rabie, Emann M., Zhang, Sherry X., Dunn, Connor E., Nelson, Celeste M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684726/ https://www.ncbi.nlm.nih.gov/pubmed/34038147 http://dx.doi.org/10.1091/mbc.E21-02-0072

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