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Cytoskeleton integrity influences XRCC1 and PCNA dynamics at DNA damage

On induction of DNA damage with 405-nm laser light, proteins involved in base excision repair (BER) are recruited to DNA lesions. We find that the dynamics of factors typical of either short-patch (XRCC1) or long-patch (PCNA) BER are altered by chemicals that perturb actin or tubulin polymerization...

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Detalles Bibliográficos
Autores principales:	Hurst, Verena, Challa, Kiran, Shimada, Kenji, Gasser, Susan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2021
Materias:	Brief Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684753/ https://www.ncbi.nlm.nih.gov/pubmed/34379448 http://dx.doi.org/10.1091/mbc.E20-10-0680

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