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Modeling a disease-correlated tubulin mutation in budding yeast reveals insight into MAP-mediated dynein function
Mutations in the genes that encode α- and β-tubulin underlie many neurological diseases, most notably malformations in cortical development. In addition to revealing the molecular basis for disease etiology, studying such mutations can provide insight into microtubule function and the role of the la...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684761/ https://www.ncbi.nlm.nih.gov/pubmed/34379441 http://dx.doi.org/10.1091/mbc.E21-05-0237 |