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Modeling a disease-correlated tubulin mutation in budding yeast reveals insight into MAP-mediated dynein function

Mutations in the genes that encode α- and β-tubulin underlie many neurological diseases, most notably malformations in cortical development. In addition to revealing the molecular basis for disease etiology, studying such mutations can provide insight into microtubule function and the role of the la...

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Detalles Bibliográficos
Autores principales: Denarier, E., Ecklund, K. H., Berthier, G., Favier, A., O’Toole, E. T., Gory-Fauré, S., De Macedo, L., Delphin, C., Andrieux, A., Markus, S. M., Boscheron, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684761/
https://www.ncbi.nlm.nih.gov/pubmed/34379441
http://dx.doi.org/10.1091/mbc.E21-05-0237