Tissue plasminogen activator rescues steroid-induced outflow facility reduction via non-enzymatic action

PURPOSE: Tissue plasminogen activator (tPA) prevents steroid-induced reduction in aqueous humor outflow facility; however, its mechanism of action at the trabecular meshwork (TM) remains unclear. Enzymatic and non-enzymatic domains allow tPA to function as both an enzyme and a cytokine. This study s...

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Detalles Bibliográficos
Autores principales: Gindina, Sofya, Barron, Arturo O., Hu, Yan, Dimopoulos, Antonios, Danias, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684809/
https://www.ncbi.nlm.nih.gov/pubmed/35002214

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