Ethyl Pyruvate Alleviates Pulmonary Hypertension through the Suppression of Pulmonary Artery Smooth Muscle Cell Proliferation via the High Mobility Group Protein B1/Receptor for Advanced Glycation End-Products Axis

Purpose: Pulmonary arterial hypertension (PAH) is a formidable disease with no effective treatment at present. With the goal of developing potential therapies, we attempted to determine whether ethyl pyruvate (EP) could alleviate PAH and its mechanism. Methods: Pulmonary smooth muscle cells were cul...

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Detalles Bibliográficos
Autores principales: Liu, Chuanzhen, Sun, Hourong, Tang, Mengmeng, Li, Jianhua, Zhang, Xiquan, Cao, Guangqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684839/
https://www.ncbi.nlm.nih.gov/pubmed/34011805
http://dx.doi.org/10.5761/atcs.oa.21-00027

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