Disseminated Histoplasmosis Involving Soft Palate, Duodenum, Sigmoid Colon and Bone Marrow in a Patient With Isolated CD4+ T-Lymphocytopenia

Idiopathic CD4 T-lymphocytopenia (ICL) is a rare entity that is associated with decreased immunity which predisposes affected individuals to opportunistic infections and malignancies. Autoimmune conditions are common in patients with ICL and they are considered part of its clinical spectrum as well....

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Autores principales: Samji, Naga Swetha, Verma, Rajanshu, Mohammed, Sanobar Y, Khan, Farhan, Ismail, Mohammad K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684889/
https://www.ncbi.nlm.nih.gov/pubmed/34938625
http://dx.doi.org/10.7759/cureus.19748
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author Samji, Naga Swetha
Verma, Rajanshu
Mohammed, Sanobar Y
Khan, Farhan
Ismail, Mohammad K
author_facet Samji, Naga Swetha
Verma, Rajanshu
Mohammed, Sanobar Y
Khan, Farhan
Ismail, Mohammad K
author_sort Samji, Naga Swetha
collection PubMed
description Idiopathic CD4 T-lymphocytopenia (ICL) is a rare entity that is associated with decreased immunity which predisposes affected individuals to opportunistic infections and malignancies. Autoimmune conditions are common in patients with ICL and they are considered part of its clinical spectrum as well. Treatment of ICL includes treatment of opportunistic infections and prophylaxis against them. Some cases are self-limited while others require long-term monitoring. We present a case of a 60-year-old man who was diagnosed with disseminated histoplasmosis involving soft palate, duodenum, colon and bone marrow in the setting of idiopathic CD4 T-lymphocytopenia.
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spelling pubmed-86848892021-12-21 Disseminated Histoplasmosis Involving Soft Palate, Duodenum, Sigmoid Colon and Bone Marrow in a Patient With Isolated CD4+ T-Lymphocytopenia Samji, Naga Swetha Verma, Rajanshu Mohammed, Sanobar Y Khan, Farhan Ismail, Mohammad K Cureus Internal Medicine Idiopathic CD4 T-lymphocytopenia (ICL) is a rare entity that is associated with decreased immunity which predisposes affected individuals to opportunistic infections and malignancies. Autoimmune conditions are common in patients with ICL and they are considered part of its clinical spectrum as well. Treatment of ICL includes treatment of opportunistic infections and prophylaxis against them. Some cases are self-limited while others require long-term monitoring. We present a case of a 60-year-old man who was diagnosed with disseminated histoplasmosis involving soft palate, duodenum, colon and bone marrow in the setting of idiopathic CD4 T-lymphocytopenia. Cureus 2021-11-19 /pmc/articles/PMC8684889/ /pubmed/34938625 http://dx.doi.org/10.7759/cureus.19748 Text en Copyright © 2021, Samji et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Samji, Naga Swetha
Verma, Rajanshu
Mohammed, Sanobar Y
Khan, Farhan
Ismail, Mohammad K
Disseminated Histoplasmosis Involving Soft Palate, Duodenum, Sigmoid Colon and Bone Marrow in a Patient With Isolated CD4+ T-Lymphocytopenia
title Disseminated Histoplasmosis Involving Soft Palate, Duodenum, Sigmoid Colon and Bone Marrow in a Patient With Isolated CD4+ T-Lymphocytopenia
title_full Disseminated Histoplasmosis Involving Soft Palate, Duodenum, Sigmoid Colon and Bone Marrow in a Patient With Isolated CD4+ T-Lymphocytopenia
title_fullStr Disseminated Histoplasmosis Involving Soft Palate, Duodenum, Sigmoid Colon and Bone Marrow in a Patient With Isolated CD4+ T-Lymphocytopenia
title_full_unstemmed Disseminated Histoplasmosis Involving Soft Palate, Duodenum, Sigmoid Colon and Bone Marrow in a Patient With Isolated CD4+ T-Lymphocytopenia
title_short Disseminated Histoplasmosis Involving Soft Palate, Duodenum, Sigmoid Colon and Bone Marrow in a Patient With Isolated CD4+ T-Lymphocytopenia
title_sort disseminated histoplasmosis involving soft palate, duodenum, sigmoid colon and bone marrow in a patient with isolated cd4+ t-lymphocytopenia
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684889/
https://www.ncbi.nlm.nih.gov/pubmed/34938625
http://dx.doi.org/10.7759/cureus.19748
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