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Hiperamonemia en paciente COVID-19 positivo. Una rara causa de alteración del estado de conciencia en pacientes sin falla hepática. Reporte de caso

A case report of COVID-19 infection in a patient presenting with upper and lower gastrointestinal and respiratory symptoms, ending in respiratory failure and the need for invasive mechanical ventilation, presenting with improvement in his respiratory and gastrointestinal symptoms, but with limitatio...

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Detalles Bibliográficos
Autores principales: Ortiz, Guillermo, Celemín, Carlos, Cortés, Aníbal, Rojas, María Catalina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asociación Colombiana de Medicina Crítica y Cuidado lntensivo. Published by Elsevier España, S.L.U. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685194/
http://dx.doi.org/10.1016/j.acci.2021.11.004
Descripción
Sumario:A case report of COVID-19 infection in a patient presenting with upper and lower gastrointestinal and respiratory symptoms, ending in respiratory failure and the need for invasive mechanical ventilation, presenting with improvement in his respiratory and gastrointestinal symptoms, but with limitations for extubation due to altered state of consciousness despite weaning from analgesia for more than 72 hours, in whom elevated levels of ammonia were found without signs of liver failure. Diarrhoea and liver involvement are frequent manifestations in patients with COVID-19, which can possibly lead to a decrease in carnitine levels and secondary hyperammonaemia, becoming a challenge for clinicians.