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Engineered synaptic tools reveal localized cAMP signaling in synapse assembly

The physiological mechanisms driving synapse formation are elusive. Although numerous signals are known to regulate synapses, it remains unclear which signaling mechanisms organize initial synapse assembly. Here, we describe new tools, referred to as “SynTAMs” for synaptic targeting molecules, that...

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Detalles Bibliográficos
Autores principales: Sando, Richard, Ho, Milan Lyndie, Liu, Xinran, Südhof, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685283/
https://www.ncbi.nlm.nih.gov/pubmed/34913963
http://dx.doi.org/10.1083/jcb.202109111