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Neutrophil extracellular traps and heparin-induced antibodies contribute to vascular access thrombosis in hemodialysis patients

BACKGROUND: Anti-heparin/platelet factor 4 (PF4) antibodies may trigger severe thrombotic complications in hemodialysis (HD) patients. Tetrameric PF4 has a high affinity for extracellular DNA, which is a key component of neutrophil extracellular traps (NETs); therefore, the interactions between anti...

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Detalles Bibliográficos
Autores principales: Lee, Hoi Woul, An, Jung Nam, Lee, Hyung Seok, Song, Young Rim, Kim, Hyung Jik, Kim, Sung Gyun, Kim, Jwa-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Nephrology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685352/
https://www.ncbi.nlm.nih.gov/pubmed/34370931
http://dx.doi.org/10.23876/j.krcp.21.080