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Protective Effects and Mechanisms of Polyethylene Glycol Loxenatide Against Hyperglycemia and Liver Injury in db/db diabetic Mice
Background: Type 2 diabetes mellitus (T2DM) is a metabolic disorder with insulin resistance and impaired insulin secretion that can cause complications, including liver injury. Polyethylene glycol loxenatide (PEG-Loxe), a glucagon-like peptide-1 (GLP-1) analog, is widely used to treat T2DM. However,...
Autores principales: | Zhang, Yu, Li, Yufeng, Zhao, Junjun, Wang, Cong, Deng, Bin, Zhang, Qilin, Shi, Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685428/ https://www.ncbi.nlm.nih.gov/pubmed/34938192 http://dx.doi.org/10.3389/fphar.2021.781856 |
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