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Protective Effects and Mechanisms of Polyethylene Glycol Loxenatide Against Hyperglycemia and Liver Injury in db/db diabetic Mice

Background: Type 2 diabetes mellitus (T2DM) is a metabolic disorder with insulin resistance and impaired insulin secretion that can cause complications, including liver injury. Polyethylene glycol loxenatide (PEG-Loxe), a glucagon-like peptide-1 (GLP-1) analog, is widely used to treat T2DM. However,...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Li, Yufeng, Zhao, Junjun, Wang, Cong, Deng, Bin, Zhang, Qilin, Shi, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685428/
https://www.ncbi.nlm.nih.gov/pubmed/34938192
http://dx.doi.org/10.3389/fphar.2021.781856

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