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Pharmacokinetics and safety/tolerability of isoniazid, rifampicin and pyrazinamide in children and adolescents treated for tuberculous meningitis

OBJECTIVE: To assess the pharmacokinetics and safety/tolerability of isoniazid, rifampicin and pyrazinamide in children and adolescents with tuberculous meningitis (TBM). DESIGN: Prospective observational pharmacokinetic study with an exploratory pharmacokinetic/pharmacodynamic analysis. SETTING: Ha...

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Detalles Bibliográficos
Autores principales:	Ruslami, Rovina, Gafar, Fajri, Yunivita, Vycke, Parwati, Ida, Ganiem, Ahmad R, Aarnoutse, Rob E, Wilffert, Bob, Alffenaar, Jan-Willem C, Nataprawira, Heda M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Drug Therapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685623/ https://www.ncbi.nlm.nih.gov/pubmed/34183327 http://dx.doi.org/10.1136/archdischild-2020-321426

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