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Endocytic proteins with prion-like domains form viscoelastic condensates that enable membrane remodeling

Membrane invagination and vesicle formation are key steps in endocytosis and cellular trafficking. Here, we show that endocytic coat proteins with prion-like domains (PLDs) form hemispherical puncta in the budding yeast, Saccharomyces cerevisiae. These puncta have the hallmarks of biomolecular conde...

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Detalles Bibliográficos
Autores principales: Bergeron-Sandoval, Louis-Philippe, Kumar, Sandeep, Heris, Hossein Khadivi, Chang, Catherine L. A., Cornell, Caitlin E., Keller, Sarah L., François, Paul, Hendricks, Adam G., Ehrlicher, Allen J., Pappu, Rohit V., Michnick, Stephen W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685726/
https://www.ncbi.nlm.nih.gov/pubmed/34887356
http://dx.doi.org/10.1073/pnas.2113789118