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Endocytic proteins with prion-like domains form viscoelastic condensates that enable membrane remodeling
Membrane invagination and vesicle formation are key steps in endocytosis and cellular trafficking. Here, we show that endocytic coat proteins with prion-like domains (PLDs) form hemispherical puncta in the budding yeast, Saccharomyces cerevisiae. These puncta have the hallmarks of biomolecular conde...
Autores principales: | Bergeron-Sandoval, Louis-Philippe, Kumar, Sandeep, Heris, Hossein Khadivi, Chang, Catherine L. A., Cornell, Caitlin E., Keller, Sarah L., François, Paul, Hendricks, Adam G., Ehrlicher, Allen J., Pappu, Rohit V., Michnick, Stephen W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685726/ https://www.ncbi.nlm.nih.gov/pubmed/34887356 http://dx.doi.org/10.1073/pnas.2113789118 |
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