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Comprehensive analysis of N6-methyladenosine (m(6)A) modification during the degeneration of lumbar intervertebral disc in mice

OBJECTIVE: To study the N6-methyladenosine (m(6)A) modification pattern of nucleus pulposus (NP) tissue during intervertebral disc degeneration (IDD). METHODS: A standing mouse model was generated, and staining and imaging methods were used to evaluate the IDD model. Methylated RNA immunoprecipitati...

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Detalles Bibliográficos
Autores principales:	Zhu, Bin, Chen, Hao-xiang, Li, Shan, Tan, Jing-hua, Xie, Yong, Zou, Ming-xiang, Wang, Cheng, Xue, Jing-bo, Li, Xue-lin, Cao, Yong, Yan, Yi-guo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Chinese Speaking Orthopaedic Society 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685911/ https://www.ncbi.nlm.nih.gov/pubmed/34976732 http://dx.doi.org/10.1016/j.jot.2021.10.008

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