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Amyloid β aggregation induces human brain microvascular endothelial cell death with abnormal actin organization

Cerebral amyloid angiopathy (CAA) is a disease in which amyloid β (Aβ) is deposited on the walls of blood vessels in the brain, making those walls brittle and causing cerebral hemorrhage. However, the mechanism underlying its onset is not well understood. The aggregation and accumulation of Aβ cause...

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Detalles Bibliográficos
Autores principales: Take, Yushiro, Chikai, Yusaku, Shimamori, Keiya, Kuragano, Masahiro, Kurita, Hiroki, Tokuraku, Kiyotaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685982/
https://www.ncbi.nlm.nih.gov/pubmed/34977364
http://dx.doi.org/10.1016/j.bbrep.2021.101189