HT-SELEX-based identification of binding pre-miRNA hairpin-motif for small molecules

Selective targeting of biologically relevant RNAs with small molecules is a long-standing challenge due to the lack of clear understanding of the binding RNA motifs for small molecules. The standard SELEX procedure allows the identification of specific RNA binders (aptamers) for the target of intere...

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Detalles Bibliográficos
Autores principales: Mukherjee, Sanjukta, Murata, Asako, Ishida, Ryoga, Sugai, Ayako, Dohno, Chikara, Hamada, Michiaki, Krishna, Sudhir, Nakatani, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685993/
https://www.ncbi.nlm.nih.gov/pubmed/34976435
http://dx.doi.org/10.1016/j.omtn.2021.11.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685993/
https://www.ncbi.nlm.nih.gov/pubmed/34976435
http://dx.doi.org/10.1016/j.omtn.2021.11.021

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