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HT-SELEX-based identification of binding pre-miRNA hairpin-motif for small molecules
Selective targeting of biologically relevant RNAs with small molecules is a long-standing challenge due to the lack of clear understanding of the binding RNA motifs for small molecules. The standard SELEX procedure allows the identification of specific RNA binders (aptamers) for the target of intere...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685993/ https://www.ncbi.nlm.nih.gov/pubmed/34976435 http://dx.doi.org/10.1016/j.omtn.2021.11.021 |