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Engineering for an HPV 9-valent vaccine candidate using genomic constitutive over-expression and low lipopolysaccharide levels in Escherichia coli cells

BACKGROUND: The various advantages associated with the growth properties of Escherichia coli have justified their use in the production of genetically engineered vaccines. However, endotoxin contamination, plasmid vector instability, and the requirement for antibiotic supplementation are frequent bo...

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Detalles Bibliográficos
Autores principales:	Wang, Kaihang, Zhou, Lizhi, Chen, Tingting, Li, Qiong, Li, Jiajia, Liu, Liqin, Li, Yuqian, Sun, Jie, Li, Tingting, Wang, Yingbin, Kong, Zhibo, Zheng, Qingbing, Zhang, Jun, Yu, Hai, Gu, Ying, Xia, Ningshao, Li, Shaowei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686089/ https://www.ncbi.nlm.nih.gov/pubmed/34930257 http://dx.doi.org/10.1186/s12934-021-01719-8

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