Liver injury associated with acute pancreatitis: The current status of clinical evaluation and involved mechanisms

Acute pancreatitis (AP) is a very common acute disease, and the mortality rate of severe AP (SAP) is between 15% and 35%. The main causes of death are multiple organ dysfunction syndrome and infections. The mortality rate of patients with SAP related to liver failure is as high as 83%, and approxima...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Wei, Du, Juan-Juan, Li, Zeng-Hui, Zhang, Xin-Yu, Zuo, Hou-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Minireviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686151/
https://www.ncbi.nlm.nih.gov/pubmed/35004974
http://dx.doi.org/10.12998/wjcc.v9.i34.10418
_version_ 1784617961137373184
author Liu, Wei
Du, Juan-Juan
Li, Zeng-Hui
Zhang, Xin-Yu
Zuo, Hou-Dong
author_facet Liu, Wei
Du, Juan-Juan
Li, Zeng-Hui
Zhang, Xin-Yu
Zuo, Hou-Dong
author_sort Liu, Wei
collection PubMed
description Acute pancreatitis (AP) is a very common acute disease, and the mortality rate of severe AP (SAP) is between 15% and 35%. The main causes of death are multiple organ dysfunction syndrome and infections. The mortality rate of patients with SAP related to liver failure is as high as 83%, and approximately 5% of the SAP patients have fulminant liver failure. Liver function is closely related to the progression and prognosis of AP. In this review, we aim to elaborate on the clinical manifestations and mechanism of liver injury in patients with AP.
format Online
Article
Text
id pubmed-8686151
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Baishideng Publishing Group Inc
record_format MEDLINE/PubMed
spelling pubmed-86861512022-01-06 Liver injury associated with acute pancreatitis: The current status of clinical evaluation and involved mechanisms Liu, Wei Du, Juan-Juan Li, Zeng-Hui Zhang, Xin-Yu Zuo, Hou-Dong World J Clin Cases Minireviews Acute pancreatitis (AP) is a very common acute disease, and the mortality rate of severe AP (SAP) is between 15% and 35%. The main causes of death are multiple organ dysfunction syndrome and infections. The mortality rate of patients with SAP related to liver failure is as high as 83%, and approximately 5% of the SAP patients have fulminant liver failure. Liver function is closely related to the progression and prognosis of AP. In this review, we aim to elaborate on the clinical manifestations and mechanism of liver injury in patients with AP. Baishideng Publishing Group Inc 2021-12-06 2021-12-06 /pmc/articles/PMC8686151/ /pubmed/35004974 http://dx.doi.org/10.12998/wjcc.v9.i34.10418 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Minireviews
Liu, Wei
Du, Juan-Juan
Li, Zeng-Hui
Zhang, Xin-Yu
Zuo, Hou-Dong
Liver injury associated with acute pancreatitis: The current status of clinical evaluation and involved mechanisms
title Liver injury associated with acute pancreatitis: The current status of clinical evaluation and involved mechanisms
title_full Liver injury associated with acute pancreatitis: The current status of clinical evaluation and involved mechanisms
title_fullStr Liver injury associated with acute pancreatitis: The current status of clinical evaluation and involved mechanisms
title_full_unstemmed Liver injury associated with acute pancreatitis: The current status of clinical evaluation and involved mechanisms
title_short Liver injury associated with acute pancreatitis: The current status of clinical evaluation and involved mechanisms
title_sort liver injury associated with acute pancreatitis: the current status of clinical evaluation and involved mechanisms
topic Minireviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686151/
https://www.ncbi.nlm.nih.gov/pubmed/35004974
http://dx.doi.org/10.12998/wjcc.v9.i34.10418
work_keys_str_mv AT liuwei liverinjuryassociatedwithacutepancreatitisthecurrentstatusofclinicalevaluationandinvolvedmechanisms
AT dujuanjuan liverinjuryassociatedwithacutepancreatitisthecurrentstatusofclinicalevaluationandinvolvedmechanisms
AT lizenghui liverinjuryassociatedwithacutepancreatitisthecurrentstatusofclinicalevaluationandinvolvedmechanisms
AT zhangxinyu liverinjuryassociatedwithacutepancreatitisthecurrentstatusofclinicalevaluationandinvolvedmechanisms
AT zuohoudong liverinjuryassociatedwithacutepancreatitisthecurrentstatusofclinicalevaluationandinvolvedmechanisms

Ejemplares similares