Integrated miRNA/cytokine/chemokine profiling reveals severity-associated step changes and principal correlates of fatality in COVID-19

Inflammatory cytokines and chemokines (CC) drive COVID-19 pathology. Yet, patients with similar circulating CC levels present with different disease severity. Here, we determined 171 microRNAomes from 58 hospitalized COVID-19 patients (Cohort 1) and levels of 25 cytokines and chemokines (CC) in the...

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Detalles Bibliográficos
Autores principales: Wilson, Julie C., Kealy, David, James, Sally R., Plowman, Tobias, Newling, Katherine, Jagger, Christopher, Filbey, Kara, Mann, Elizabeth R., Konkel, Joanne E., Menon, Madhvi, Knight, Sean B., Simpson, Angela, Prihartadi, Aliya, Forshaw, Greg, Todd, Neil, Yates, David R.A., Grainger, John R., Hussell, Tracy, Kaye, Paul M., Signoret, Nathalie, Lagos, Dimitris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686203/
https://www.ncbi.nlm.nih.gov/pubmed/34957382
http://dx.doi.org/10.1016/j.isci.2021.103672

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